STUDIES ON THE TOTAL INTAKE SIMULANT DMMPA

Authors
  1. Adie, P.A.
  2. McNally, W.D.
Corporate Authors
Defence Research Establishment Suffield, Ralston ALTA (CAN)
Abstract
Dimethyl morpholinophosphoramidate (DMMPA) has been tested for suitability as a simulant for chemical agents in studying the effectiveness of chemical defence procedures. Results show that it is easily detected in urine after percutaneous, oral and intramuscular administration. The compound is shown to have very low toxicity when administered acutely in mice. Twenty-eight days of application to the skin of rats and rabbits produced no evidence of damage to the skin. DMMPA is concluded to be useful and safe as a total intake simulant. Tests done with rats, mice and rabbits.
Report Number
TP-469 —
Date of publication
15 Aug 1977
Number of Pages
14
DSTKIM No
77-03807
CANDIS No
100499
Format(s):
Hardcopy;Originator's fiche received by DSIS

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