OXYHEMOGLOBIN SATURATION FOLLOWING RAPID DECOMPRESSION TO 18,288 m PRECEDED BY DILUTED OXYGEN BREATHING

Authors
  1. Buick, F.
  2. Porlier, J.A.G.
Corporate Authors
Defence and Civil Inst of Environmental Medicine, Downsview ONT (CAN)
Abstract
The investigation studied oxyhemoglobin saturation (SaO2) and cardiovascular indices after rapid decompression (RD). Before RD, fractional inspired O2 concentration (FiO2) simulated the range of product gas from molecular sieve O2 generating systems (MSOGS). Four subjects breathed 1.0-0.80 FiO2 at 6,858 m. After decompression to 18,288 m, the subject received 1.0 FiO2 at a positive pressure of 70 mm Hg for 3 min. There were no incidents of severe hypoxia. The mean SaO2 was 98.0% before RD. After RD, SaO2 was maintained at the pre-RD level for 8 s, decreased rapidly over the next 10 s, and over the rest of the 1st min decreased more gradually to reach approximately 82%. Varying FiO2 before RD had no effect on the alteration in SaO2, heart rate, stroke index, and blood pressure after RD. The MSOGS O2 product range offers adequate protection against hypoxia during RD to 18,288 m.
Report Number
DCIEM-91-67 — Research Paper (Final); Reprint
Date of publication
15 Jul 1991
Number of Pages
6
Reprinted from
Aviat Space Environ Med, vol 62, no 12, 1991, p 1119-1126
DSTKIM No
92-00731
CANDIS No
103625
Format(s):
Hardcopy;Originator's fiche received by DSIS

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