EVALUATION OF DETECTORS, CHEMICAL AGENT, NERVE VAPOUR MADE WITH EEL ACETYLCHOLINESTERASE

Authors
  1. Preston, J.M.
  2. Bovenkamp, J.W.
Corporate Authors
Defence Research Establishment Ottawa, Ottawa ONT (CAN)
Abstract
The manufacturer of the Detector, Chemical Agent, Nerve Vapour has at times encountered difficulty in obtaining bovine acetylcholinesterase of the required activity and purity. As an alternative, detectors were manufactured using a simple substitution of eel acetylcholinesterase for bovine. The performance of eel- and bovine-enzyme detectors was compared with respect to known concentrations of GB and GD in air and to VX and GD in water. The detectors were subjected to accelerated storage trials. The results show that the detectors manufactured with eel acetylcholinesterase compare favourably to those manufactured with bovine. A recommendation is made that the specification for the Detector, Chemical Agent, Nerve Vapour be changed to allow the use of eel acetylcholinesterase.
Report Number
TN-82-33 —
Date of publication
15 Sep 1983
Number of Pages
13
DSTKIM No
84-01880
CANDIS No
121277
Format(s):
Hardcopy;Originator's fiche received by DSIS

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