AIRBORNE TESTING OF THREE ANTIMOTION SICKNESS PREPARATIONS

Authors
  1. Johnson, W.H.
  2. Money, K.E.
  3. Graybiel, A.
Corporate Authors
Defence and Civil Inst of Environmental Medicine, Downsview ONT (CAN)
Abstract
Thirteen human volunteers were exposed to weekly flights in which standardized, steep turns were used to produce motion sickness. A combination of promethazine hydrochloride (25 mg) plus ephedrine sulphate (25 mg) was found to be equally as effective as the combination of 1-scopolamine hydrobromide (0.35 mg) plus d-amphetamine sulphate (5 mg). Droperidol (2.5 mg) was indistinguishable from the placebo. It was concluded that the treatment of choice for motion sickness is promethazine plus ephedrine.
Report Number
76-X-41 —
Date of publication
01 Jan 1976
Number of Pages
3
Reprinted from
Aviation, Space, and Environmental Medicine, vol 47, no 11, 1976, p 1214-1216
DSTKIM No
77-00985
CANDIS No
123951
Format(s):
Hardcopy

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