STEROIDS. III: THE EPIMERIC N-ACETYL-3-AMINOCHOLEST-4- AND -5-ENES

Authors
  1. Bannard, R.A.B.
  2. McKay, A.F.
Corporate Authors
Defence Research Chemical Labs, Ottawa ONT (CAN)
Abstract
Lithium aluminum hydride reduction of the oximes of 3-ketocholest-4- and -5-enes gave mixtures of amines. These amines on acetylation and separation gave respectively N-acetyl-3(alpha)-aminocholest-5-ene, N-acetyl-3(beta) aminocholest-5-ene, N-acetyl-3(alpha)-aminocholest-4-ene, and N-acetyl-3(beta)-aminocholest-4-ene. The N-acetyl-3(alpha)-aminocholest-5-ene (m.p. 184.5C.) was shown to be identical with the cholesterylacetamide obtained by the acetylation of the degradation product from N-benzyl-3(alpha)-aminocholest-5-ene (m.p. 90-91C.).
Report Number
DRCL-172 — Reprint; Previously accessioned as DSIS 55/12438
Date of publication
15 Mar 1955
Number of Pages
7
Reprinted from
Canadian J of Chemistry, vol 33, 1955, p 1166-1170
DSTKIM No
92-03699
CANDIS No
127049
Format(s):
Hardcopy;Originator's fiche received by DSIS

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