Concept for an expedient biological agent detector

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Authors
  1. McFee, J.E.
  2. Lee, W.E.
Corporate Authors
Defence Research Establishment Suffield, Ralston ALTA (CAN)
Abstract
The report presents a Canadian proposal, submitted to ITF-19 of the US/UK/CA Memorandum of Understanding on Chemical and Biological Defensive Materiel, for a biological agent detector which could be felded by 1995. The proposed system consists of an aerosol particle sizer (APS) and large volume air sampler for non-specific detection and collection/preconcentration. Flow cytometry is used for generic detection. Specific detection is achieved using the advanced concept model (ACM) of the BCD biochemical detector. A Threshold Unit and a standard ELISA immunoassay are used as backups. An alternate system is also proposed if more development time is available beyond the ITF-19 mandate. In it, the standard APS is replaced by one which uses an ultraviolet source to discriminate particles of biological origin from background by fluorescence. Specific detection is achieved by surface plasmon resonance (SPR). The report also describes the results of Canada's original prescreening of technologies, and gives a detailed analysis both of the subtechnologies which comprise the proposed system and of the total system. A description of the current Canadian biodetector, the MASU/MAGIDU, is also given.
Keywords
Surface plasmon resonance;LAP (Light Addressable Potentiometry)
Report Number
DRES-M-1399 — Memorandum
Date of publication
01 Jan 1993
Number of Pages
61p
DSTKIM No
93-01473
CANDIS No
129713
Format(s):
Hardcopy;Originator's fiche received by DSIS;Document Image stored on Optical Disk

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