SEPARATION AND DETECTION OF LEWISITE BY SUPERCRITICAL FLUID CHROMATOGRAPHY AND GAS CHROMATOGRAPHY

Authors
  1. Fuhr, B.J.
  2. Holloway, L.
  3. Klein, L.
Corporate Authors
Defence Research Establishment Suffield, Ralston ALTA (CAN);Alberta Research Council, Edmonton ALTA (CAN)
Abstract
Lewisite, an arsenic containing chemical warfare agent (CWA) is identified on Schedule (1) of the Annex to Article VI of the developing Chemical Weapons Convention (CWC). The CWC requires routine monitoring of the single small scale facilities in addition to the verification of non-production and destruction of CW agents and investigation of allegations of first use of lewsite. For this reason sensitive and specific detection methods are needed. In the present study the main objective was to examine the SFC technique employing capillary columns, since it would potentially allow analysis of lewsite directly without the need for derivatization. When this approach failed due to the instability of the lewsite, a more thorough investigation of the derivatization technique with analysis by both GC and SFC was undertaken.
Report Number
DRES-CR-93-09 — Contract Report (Final)
Date of publication
01 Dec 1991
Number of Pages
31
DSTKIM No
93-02110
CANDIS No
129896
Format(s):
Hardcopy;Originator's fiche received by DSIS

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