CAPILLARY COLUMN GC-MS/MS CONFIRMATION OF PHOSPHATE ESTERS WITH A HYBRID TANDEM MASS SCPECTROMETER

Authors
  1. D'Agostino, P.A.
Corporate Authors
Defence Research Establishment Suffield, Ralston ALTA (CAN)
Abstract
Daughter, parent, constant neutral loss and multiple reaction ion monitoring were all evaluated for the detection and confirmation of phosphate esters during capillary column GC-MS/MS analysis with a hybrid tandem mass spectrometer. Constant neutral loss and parent modes involve scanning of the sector, thus reducing the benefits of higher sector resolution, while daughter and multiple reaction ion monitoring data may be acquired with higher sector resolution. The benefit of sector resolution was demonstrated for the detection and confirmation and phosphate esters in the presence of diesel exhaust extract components present at levels several orders of magnitude above that of the phosphate esters. Detection limits for daughter operation were approximately the same as those obtained during capillary column GC-MS analysis of standards under electron impact ionization, and S/N rations in excess of 100:1 were observed during multiple reaction ion monitoring of the diesel exhaust extract spiked at the 200 pg level with phosphate esters.
Report Number
DRES-M-1400 — Memorandum
Date of publication
01 Feb 1994
Number of Pages
36
DSTKIM No
94-02376
CANDIS No
141343
Format(s):
Hardcopy;Originator's fiche received by DSIS

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