CAPILLARY COLUMN GAS CHROMATOGRAPHY - TANDEM MASS SPECTROMETRIC CHARACTERIZATION OF IRRITANTS

PDF

Authors
  1. D'Agostino, P.A.
  2. Provost, L.R.
Corporate Authors
Defence Research Establishment Suffield, Ralston ALTA (CAN)
Abstract
Daughter spectra were obtained for the molecular and principal electron impact fragmentation ions of four irritants, 1-methoxycycloheptatriene, 2-chloroacetophenone, o-chlorobenzylidenemalononitrile and dibenz(b,f)-1,4-oxazepin, during capillary column GC-MS/MS analysis. The use of standardized collisional activated dissociation cell conditions resulted in the acquisition of reproducible daughter spectra suitable for identification and data-base generation purposes. Daughter operation detection limits of 100 pg (S/N > 10:1), for the highest molecular weight irritant, dibenz(b,f)-1,4-oxazepin, were obtained. This level of sensitivity was approximately the same as that routinely obtained for other chemical warfare agents during capillary column GC-MS analysis of standards under electron impact ionization conditions.
Keywords
Methoxycycloheptatriene;Chloroacetophenone;Chlorobenzylidenemalononitrile;Dibenz[b,f]-1,4-oxazepin;Capillary column GC-MS/MS analysis;Tandem mass spectrometry
Report Number
DRES-M-1445 — Memorandum
Date of publication
01 Jan 1995
Number of Pages
19
DSTKIM No
95-01592
CANDIS No
150324
Format(s):
Hardcopy;Document Image stored on Optical Disk

Permanent link

Document 1 of 1

Date modified: