EVALUATION OF THE RES-Q-AIR INHALATION REWARMING SYSTEM ON NON-SHIVERING HYPOTHERMIC SUBJECTS

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Authors
  1. Ducharme, M.B.
  2. Goheen, S.L.
  3. Giesbrecht, G.G.
  4. Frim, J.
  5. Johnston, C.E.
  6. Kenny, G.L.
Corporate Authors
Defence and Civil Inst of Environmental Medicine, Downsview ONT (CAN)
Abstract
The objective of the present study was to test the efficacy of inhalation rewarming (IR) in simulated field conditions using a newly developed model of non-shivering hypothermia in humans. Eight subjects (2 of them female) were cooled in 8-10C water for 25 min on two occasions. Ten minutes prior to withdrawal from the water, a total of 1.5 mg.kg 1(-) of Meperidine, a shivering inhibitor, was injected intravenously into the subjects. The subjects were then removed from the water, settled in a sleeping bag and moved to a cold chamber set at -20C for a 2.5 hour rewarming period. In the control trial, no external source of heat was available to the subject while in the IR trial, IR was provided (water saturated air at 43C). In both trials, shivering was successfully suppressed since the metabolic rates during the rewarming phases were not differnt from baseline values. The duration and magnitude of the post-exposure decrease in esophageal temperature (afterdrop) were not different between the control (78 + or - 11 min; 1.4 + or - 0.1C) and the IR trials (76 + or - 10 min; 1.2 + or - 0.2C). The rates of rewarming were not different between the two treatments (0.4 + or - 0.1 C.h 1 (-) for control; 0.2 + or - 0.1C.h 1(-) for IR). After the 2.5 hr rewarming phase, the esophageal temperature did not return to the pre-immersion level for either treatment (35.79 + or - 0.17C for control; 35.85 + or - 0.13C for IR). TRUNCATED
Keywords
Meperidine;Inhalation Rewarming Treatment;Res-Q-Air IR System
Report Number
DCIEM-95-48 — Research Report
Date of publication
01 Nov 1995
Number of Pages
27
DSTKIM No
96-01249
CANDIS No
155542
Format(s):
Document Image stored on Optical Disk;Hardcopy

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