CHANGES IN THE HEMOSTATIC SYSTEM AND IN BLOOD AND URINE CHEMISTRY OF HUMAN SUBJECTS FOLLOWING DECOMPRESSION FROM A HYPERBARIC ENVIRONMENT

Authors
  1. Philp, R.B.
  2. Ackles, K.N.
  3. Inwood, M.
  4. and others
Corporate Authors
Defence and Civil Inst of Environmental Medicine, Downsview ONT (CAN);University of Western Ontario, London ONT (CAN) Dept of Pharmacology
Abstract
Sixteen human subjects were exposed to a total pressure of 10 ATA for 10 min breathing air and were then decompressed according to a continuous profile. Blood and urine parameters before and after the dive were compared for each subject. Four persons were asymptomatic and 12 reported symptoms including pruritis in all 12, Type I bends requiring recompression in three, swollen axillary lymph nodes in two and joint pain several hours later in one. The following statistically significant changes were noted in all divers: increased packed-cell volume, hemoglobin concentration, plasma free fatty acids and prothrombin time; decreased platelet counts (-10-12%), plasma cortisol (-30%), complement activity (-20%), serum lactate, euglobulin lysis time and prothrombin consumption time. The group with symptoms showed statistically significant increases in reticulocyte count, megathrombocyte index, fibrin degradation products and platelet adhesiveness and significant decreases in serum sodium a
Report Number
RP-819 — Research Report
Date of publication
01 Jan 1972
Number of Pages
8
Reprinted from
Aerospace Medicine, vol 43, no 5, 1972, p 498-505
DSTKIM No
72-05461
CANDIS No
15823
Format(s):
Hardcopy

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