THE EFFECTS OF WASHING, EDTA, MAGNESIUM AND CALCIUM ON OXIDATIVE PHOSPHORYLATION AND RESPIRATORY RATES OF MITOCHONDRIA FROM HEAT- AND COLD-ACCLIMATED RATS

Authors
  1. McBurney, L.J.
  2. Radomski, M.W.
Corporate Authors
Defence and Civil Inst of Environmental Medicine, Downsview ONT (CAN)
Abstract
The ADP/O ratios of single-sedimented liver mitochondria from heat-acclimated Sprague-Dawley rats were greater than control and cold-acclimated ratios. These differences were abolished by washing the mitochondria. EDTA in the homogenate reduced to a greater extent the magnesium and calcium content in mitochondria of cold- than heat- acclimated preparations. Elevation of magnesium in the medium increased ADP/O values and reduced respiratory rates in all mitochondrial populations. During calcium respiration ADP/O ratios were decreased most significantly in cold-acclimated mitochondria.
Report Number
RP-863 — Research Paper
Date of publication
01 Jan 1973
Number of Pages
15
Reprinted from
Comp. Biochem. Physiol., vol 44B, 1973, p 1219-1233
DSTKIM No
73-05183
CANDIS No
19994
Format(s):
Hardcopy

Permanent link

Document 1 of 1

Date modified: