NARCOTIC EFFECTS IN MAN OF BREATHING 80-20 ARGON-OXYGEN AND AIR UNDER HYPERBARIC CONDITIONS

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Authors
  1. Fowler, B.
  2. Ackles, K.N.
Corporate Authors
Defence and Civil Inst of Environmental Medicine, Downsview ONT (CAN);York Univ, Toronto ONT (CAN)
Abstract
The qualitative and quantitative effects of breathing 80-20 argon-oxygen and air were compared at the surface and at 4 and 7 ATA with 10 subjects using three measures -- mental arithmetic, subjective estimates of narcosis and an adjective checklist. Both the mental arithmetic task and the subjective estimates of narcosis indicated that the argon-oxygen mixture was more narcotic than air. Similar types of adjectives were used to describe the subjective effects of both mixtures. It was concluded that the qualitative effects of argon and nitrogen were the same on the various measures of narcosis but the discrepancy between the dose response functions for various measures raises questions about the usefulness of quantitative differences between the inert gases as indicators of underlying causal mechanisms of narcosis.
Report Number
RP-855 — Research Paper
Date of publication
01 Jan 1975
Number of Pages
6
Reprinted from
Aerospace Medicine, vol 43, no 11, 1972, p 1219-1224
DSTKIM No
73-05186
CANDIS No
19997
Format(s):
Hardcopy;Electronic Document(PDF)

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