EFFECTS OF AGE AND COLD EXPOSURE ON THE SIZE AND FUNCTIONAL ACTIVITY OF PARATHYROID GLANDS OF RATS

Authors
  1. Holness, D.E.
Corporate Authors
Defence and Civil Inst of Environmental Medicine, Downsview ONT (CAN)
Abstract
Several studies have evaluated the effect of low environmental temperature on calcium metabolism in animals. Whereas these studies suggested that cold exposure induces alterations in the metabolism of calcium, no attempt has as yet been made to appraise the effect of cold on the glands which are primarily responsible for regulating the level of calcium in the circulation, viz., the parathyroids. The study was undertaken to examine the effect of cold exposure on the size and functional activity of the parathyroid glands. The functional activity of the parathyroid glands was assessed in vivo by measuring the concentrative uptake by the parathyroids of o-aminoisobutyric acid (AIB), a non-metabolized amino acid analog. AIB uptake has been used for studies of parathyroid gland activity, and has been shown to be a function of the total calcium concentration of the serum.
Report Number
RP-864 —
Date of publication
01 Jan 1972
Number of Pages
5
Reprinted from
Int J Biometeor, vol 16, no 3, 1972, p 277-281
DSTKIM No
73-05343
CANDIS No
20121
Format(s):
Hardcopy

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