PHASE IV VOLUME OF THE SINGLE-BREATH NITROGEN WASHOUT CURVE ON EXPOSURE TO ALTITUDE

Authors
  1. Gray, G.W.
  2. Rennie, I.D.B.
  3. Houston, C.S.
  4. Bryan, A.C.
Corporate Authors
Defence and Civil Inst of Environmental Medicine, Downsview ONT (CAN)
Abstract
Phase IV volumes of the single-breath nitrogen washout curve were measured as an index of pulmonary interstitial fluid volume at ground level and after exposure to altitude. In a 4-hr exposure to 16,000 ft in a decompression chamber, no significant change was found in the phase IV volume or the phase IV/vital capacity ratio, in five subjects. In 12 subjects exposed to 17,500 ft on Mount Logan, no significant change was seen in phase IV volumes after 1 week. It is concluded that no measurable increase in the pulmonary interstitial fluid volume, as detected by this technique, occurred with altitude exposure at the time intervals in which it was measured.
Report Number
RP-909 — Research Paper
Date of publication
01 Jan 1973
Number of Pages
4
Reprinted from
J of Applied Physiology, vol 35, no 2, 1973, p 227-230
DSTKIM No
74-02287
CANDIS No
22254
Format(s):
Hardcopy

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