EFFECT OF BENZODIAZEPINE DERIVATIVES ON SOMAN-INDUCED SEIZURE ACTIVITY AND CONVULSIONS IN THE MONKEY
- Authors
- Corporate Authors
- Defence Research Establishment Suffield, Ralston ALTA (CAN)
- Abstract
- The effect of clonazepam and nitrazepam upon soman-induced seizure activity and convulsions was studied in the monkey. Intravenous administration of either of these drugs, after the onset of the activity, effectively terminated the convulsions and suppressed the seizure activity. Administration of diazepam, clonazepam or nitrazepam prior to exposure of soman prevented the onset of seizure activity and convulsions with clonazepam and nitrazepam having the longest effective duration.
- Report Number
- TP-399 —
- Date of publication
- 01 Jan 1973
- Number of Pages
- 8
- Reprinted from
- Archives Internationales de Pharmacodynamie de Th rapie, vol 202, no 2, 1973, p 244-251
- DSTKIM No
- 75-00189
- CANDIS No
- 24183
- Format(s):
- Hardcopy
Document 1 of 1
- Date modified: