THE MECHANISM OF POSITIONAL ALCOHOL NYSTAGMUS

Authors
  1. Money, K.E.
  2. Myles, W.S.
  3. Hoffert, B.M.
Corporate Authors
Defence and Civil Inst of Environmental Medicine, Downsview ONT (CAN)
Abstract
Positional alcohol nystagmus phase I (PAN I) results from a physical action of alcohol on the cupola of the semicircular canal. The evidence for this view is outlined, including findings that discrete surgical elimination of semicircular canal function eliminates alcohol nystagmus, that ingestion of heavy water (deuterium oxide) causes a postional nystagmus precisely opposite to PAN I, and the ingestion of heavy water with alcohol in cats prevents the occurrence of PAN I. New data is presented showing that ingested alcohol does enter perilymph and endolymph.
Report Number
RP-1020 — Research Paper
Date of publication
01 Jan 1974
Number of Pages
13
Reprinted from
Canadian J of Otolaryngology, vol 3, no 3, 1974, p 301-313
DSTKIM No
75-01144
CANDIS No
24809
Format(s):
Hardcopy

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