THE REGULATION OF GROWTH HORMONE SECRETION DURING DIFFERENT PHYSIOLOGIC STATES. INFLUENCE OF PHYSICAL ACTIVITY, ALPHA-ADRENERGIC BLOCKADE AND CORE TEMPERATURE CLAMPING

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Authors
  1. Cross, M.C.
Corporate Authors
Defence and Civil Inst of Environmental Medicine, Downsview ONT (CAN);Toronto Univ, Toronto ONT (CAN) Dept of Community Health
Abstract
The objectives of this thesis were to examine the regulation of GH secretion during different physiologic stimuli, such as physical activity, alpha-adrenergic blockade and alterations in core temperature. Specifically, we studied the GH response to several resistance exercise protocols, with load and frequency of repetition variation, were completed during the infusion of the alpha-adrenergic blocvker, phentolamine. We have also investigated the effect of core temperature during moderate intensity aerobic exercise on the subsequent responses of GH and selective immune system parameters. The findings of this thesis implicate a number of factors in the responses of GH to exercise, such as the alpha-adrenergic nervous system, products of accelerated glycolysis and the increase in core temperature that is observed during exercise. We also report a technique developed to separate the effects of metabolic heat production from that of energy expenditure during exercise, on the hormonal, immune and metabolic responses to a physical stressor.
Keywords
Human Growth Hormone (HGH);Phentolamine;Muscle volume;Heavy resistance exercise;Core temperature
Report Number
DCIEM-96-CR-02 — Master's Thesis; Contract Report (Final)
Date of publication
11 Jun 1996
Number of Pages
300
DSTKIM No
96-02999
CANDIS No
498757
Format(s):
Hardcopy;Document Image stored on Optical Disk

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