EFFECTS OF COMBINED CAFFEINE AND EPHEDRINE INGESTED WITH A LIQUID MEAL ON SUBSEQUENT EXERCISE PERFORMANCE

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Authors
  1. Bell, D.G.
  2. Jacobs, I.
  3. Zamecnik, J.
Corporate Authors
Defence and Civil Inst of Environmental Medicine, Downsview ONT (CAN)
Abstract
The combination of caffeine (C), and ephedrine (E) has been reported to have an ergogenic effect on high intensity aerobic exercise performance (Bell et al., 1995). A serious problem encountered with this treatment is that 25% of the subjects experienced vomiting and nausea while engaging in hard exercise after the treatment. The present study was undertaken to investigate whether food ingestion would alleviate the problem and to see if the ergogenic effect of the drugs on aerobic performance could be maintained. Thirteen healthy untrained subjects, 6 males and 7 females, completed 2 randomized and double blind, cycle ergometer trials to exhaustion at a power output equivalent to the difference 85% VO2 peak 1.5 hours after ingesting C (5 mg.kg 1(-)) and E (1 mg.kg 1(-)), or a placebo (P). The meal, a can of ENSURE PLUS (TRADEMARK), was given to the subject to drink 30 minutes after drug or placebo ingestion. Each trial was separated by one week. Venous blood samples were obtained and analyzed for caffeine and ephedrine levels pre- and 1.5 hours post-drug ingestion. VO2, VCO2, VE, and RQ were measured every minute throughout the exhaustion ride. Heart rate was also monitored during the exercise session and the final heart rate recorded. Blood drug levels (mean + or - SD) of caffeine and ephedrine immediately before the exhaustion ride were 51.9 mu M (+ or - 21.4) and 0.434 mu M (+ or - 0.127). TRUNCATED
Keywords
Ergogenic aids;VO2 max
Report Number
DCIEM-97-R-06 —
Date of publication
01 Feb 1997
Number of Pages
14
DSTKIM No
97-01976
CANDIS No
502153
Format(s):
Hardcopy;Document Image stored on Optical Disk

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