MUSCLE OXYGENATION AND PERFORMANCE DURING LOW LEVEL CARBON MONOXIDE HYPOXIA

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Authors
  1. King, C.E.
Corporate Authors
Defence and Civil Inst of Environmental Medicine, Downsview ONT (CAN);Queen's Univ, Kingston ONT (CAN) School of Rehabilitation Therapy
Abstract
This contract examined the effects of low level carbon monoxide exposure on skeletal muscle function in mongrel dogs. Three studies were performed. The first examined the impairment in muscle function with 10% or 25% carboxyhemoglobin (COHb) levels during stimulation intensities equivalent to 12% or 25% of maximum oxygen consumption. No changes in oxygen delivery or muscle tension development were observed. During the second study, the contraction stimulation was increased to represent 50% of maximum. The findings suggested that muscle function was impaired with 10% COHb level during stimulation. In an attempt to counteract this decrement, the next study compared muscle function following an induced respiratory alkalosis. The results failed to show an improvement in muscle function.
Keywords
Muscle function;Metabolic alkalosis;Respiratory alkalosis;Muscle lactate
Report Number
DCIEM-97-CR-01 — Contractor Report
Date of publication
01 Jan 1997
Number of Pages
101
DSTKIM No
97-02143
CANDIS No
502304
Format(s):
Hardcopy;Document Image stored on Optical Disk

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