SELF-MONITORING COGNITIVE PERFORMANCE DURING SLEEP DEPRIVATION: EFFECTS OF MODAFINIL, D-AMPHETAMINE AND PLACEBO

PDF

Authors
  1. Baranski, J.V.
  2. Pigeau, R.A.
Corporate Authors
Defence and Civil Inst of Environmental Medicine, Downsview ONT (CAN)
Abstract
Self-monitoring refers to the ability to assess accurately one's own performance in a specific environment. The present study investigated the effects of the stimulating drugs modafinil (300 mg) and d-amphetamine (20 mg) on the ability to self-monitoring cognitive performance during 64 h of sleep deprivation (SD) and sustained metal work. Two cognitive tasks were investigated: a visual (perceptual) judgment task and a complex mental addition task. Subjects in the placebo condition displayed marked circadian and SD effects on cognitive task performance but their self-monitoring was substantively undisturbed by SD. Subjects performing under the influence of d-amphetamine likewise displayed highly proficient self-monitoring throughout the SD period. In contrast, modafinil had a disruptive effect on self-monitoring, inducing a reliable 'overconfidence' effect (i.e. an overestimation of actual cognitive performance), which was particularly marked 2-4 h post-dose. Although modafinil has proven to be a safe and effective countermeasure to the effects of extensive SD on cognitive task performance, we encourage a more comprehensive understanding of the relation between its subjective and performance enhancing effects before the drug is recommended as a viable fatigue countermeasure.
Keywords
Modafinil;Sustained operations
Report Number
DCIEM-96-RP-09 — Research Paper
Date of publication
29 Feb 1996
Number of Pages
8
Reprinted from
European Sleep Research Society, J. Sleep Res., vol 6, 1997, p 84-91
DSTKIM No
98-00041
CANDIS No
506697
Format(s):
Hardcopy;Document Image stored on Optical Disk

Permanent link

Document 1 of 1

Date modified: