Part I: Development of an animal model to investigate the 2D and 3D high image resolution ultrasonic technology using synthetic aperture and adaptive beamformers

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Authors
  1. Suntres, Z.E.
  2. Stergiopoulos, S.
Corporate Authors
Defence R&D Canada - Toronto, Toronto ONT (CAN)
Abstract
In recent years, it has been demonstrated that the current ultrasound imaging system may be unreliable due to its poor imaging quality; in several instances, it lacks clarity, specificity, resolution and sensitivity. These disadvantages have negative consequences when diagnosing patients since false-positive or false-negative results are sometimes inescapable. It is therefore of great importance to design an ew ultrasound imaging system that is able to enhance the images provided by the current technology and subsequently prevent chances for misdiagnosis. An animal model of organ injuries has been established where the current technology in ultrasonography will be tested and compared to the newly developed 3-D ultrasound technology. For this, the effect of lipopolysaccharide (LPS), a bacterial cell wall component, was more or less injurious to all organs examined as evidenced by an increase in organ weights. In addition, a significant increae in lipid peroxidation as well as reduction in glutathione levels in tissue homogenates, confirmed the involvement of oxidative stress as a major mechanism of LPS-induced tissue injury.

Il y a un résumé en français ici.

Keywords
Medical Tomography Imaging;Ultrasonic frequencies;Ultrasound systems;3D ultrasound;Organs(anatomy)
Report Number
DRDC-TORONTO-TR-2002-023 — Technical Report
Date of publication
01 Apr 2002
Number of Pages
26
DSTKIM No
CA020775
CANDIS No
517518
Format(s):
Hardcopy;Document Image stored on Optical Disk

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