The Impact of Malarone and Primaquine on Psychomotor Performance

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Authors
  1. Paul, M.P.
  2. McCarthy, A.E.
  3. Gibson, N.
  4. Kallander, K.
  5. Kenny, G.
  6. Cook, T.
  7. Gary Gray
Corporate Authors
Defence R&D Canada - Toronto, Toronto ONT (CAN)
Abstract
Recent evidence has established the effectiveness of Malarone® and Primaquine® for chemoprophylaxis against Plasmodium falciparum malaria. Both have the advantage of providing causal prophylaxis and therefore require continued dosing for only one week after departure from a malaria endemic area. Canadian Forces aircrews are often placed in situations that put them at risk for malaria infection but the safety of these drugs for use in aircrew has not been ascertained. This study was undertaken to determine whether or not Malarone® or Primaquine® impact on psychomotor performance.

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Keywords
Malarone;Primaquine;Aircrew;Adverse effects;Psychomotor performance;Side effects
Report Number
DRDC-TORONTO-SL-2002-193 — Scientific Literature
Date of publication
01 Jul 2003
Number of Pages
8
Reprinted from
Aviation, Space, and Environmental Medicine, vol 74, no 7, p 738-745
DSTKIM No
CA023170
CANDIS No
520370
Format(s):
Electronic Document(PDF);CD ROM

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