THE EFFECT OF MILD HYPOXIA ON THE VESTIBULAR EVOKED RESPONSE

Authors
  1. Fraser, W.D.
  2. Black, N.
  3. Eastman, D.E.
  4. Landolt, J.P.
Corporate Authors
Defence and Civil Inst of Environmental Medicine, Downsview ONT (CAN)
Abstract
The effect of hypoxia on the long-latency vestibular evoked response (VsER) was examined in 8 sitting subjects who underwent intermittent 0.1 Hz sinusoidal rotation in complete darkness, while fixating on a small target light that rotated with the subject. Evoked responses were recorded during 10 minutes of rotational stimulation after breathing each gas mixture for a minimum of 25 minutes. For intermittent clockwise (CW) rotation in the horizontal plane, a reproducible negative potential (-28.7 + or - 2.3 muV) developed at electrode sites located between the vertex and the "linked" ears during air breathing conditions. It peaked close to the point of maximum velocity of the sinusoidal stimulus. This negative cortical potential decreased (i.e., it became less negative) with respect to the air control by 25.4% (P < 0.01 ) when the subjects were exposed to a 16.7% oxygen breathing mixture (altitude equivalent of 1900m). TRUNCATED
Report Number
DCIEM-87-RR-11 — Research Report; Paper to be included in Proceedings of AGARD Aerospace Medical Panel Symposium on Electric and Magnetic Activity of the Central Nervous System, 1987
Date of publication
01 Jan 1987
Number of Pages
27
DSTKIM No
87-03504
CANDIS No
52295
Format(s):
Hardcopy;Originator's fiche received by DSIS

Permanent link

Document 1 of 1

Date modified: