Characterization of Nanoparticles by Capillary Electrophoresis and Trapping of Nanoparticles in Microfluidics Device – Final Report

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Authors
  1. Tang, T.
  2. Jemere, A.B.
  3. Man, D.C.W.
Corporate Authors
Defence R&D Canada - Suffield, Ralston ALTA (CAN);Canada West Biosciences, Calgary ALTA (CAN)
Abstract
The contractor report describes research performed for Contract No. W7702-04R-021. The work was carried out in support of CRTI 03-005RD. The report describes the use of capillary electrophoresis (CE) as an analytical method for characterizing gold, polymer and iron oxide nanoparticles (NPs). The analyte species were detected by UV/vis or laser-induced fluorescence (LIF) spectroscopy. For analytes that possessed neither UV/vis absorbance nor LIF, indirect methods of detection were employed whereby a signal-generating molecular species was added to the running buffer. NPs from a variety of commercial sources and from custom syntheses were studied. The report demonstrates that CE is a valuable tool in NP research. The report also demonstrates the feasibility of trapping nanoparticles in microfluidic devices for sample clean up and detection.
Keywords
Nanotechnology;Laser-induced fluorescence;Capillary electrophoresis;Microfluidics;Nanoparticles
Report Number
DRDC-SUFFIELD-CR-2009-177 — Contractor Report
Date of publication
01 Aug 2009
Number of Pages
30
DSTKIM No
CA033494
CANDIS No
532962
Format(s):
Electronic Document(PDF)

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