Forensic Analysis of Human DNA from Samples contaminated with Bioweapons Agents

Analyse médico-légale de l’ADN humain à partir d’échantillons contaminés par des agents utilisés comme armes biologiques

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Authors
  1. Timbers, J.
  2. Wright, K.
Corporate Authors
Defence R&D Canada - Centre for Security Science, Ottawa ONT (CAN);Royal Canadian Mounted Police, Forensic Science and Identification Service
Abstract
The purpose of this research project was to further characterize and improve a preliminary protocol for removal of bacterial agents and toxins from samples that would undergo DNA analysis. The protocol must result in samples that are free of infectious or toxic material, but still generate DNA of adequate quantity and quality to meet RCMP standards for identification based on DNA. In order to obtain and identify possible criminals from DNA evidence, human samples must undergo various steps to isolate and analyse the DNA in a forensic laboratory. These steps consist of (1) the isolation of DNA from samples collected at the crime scene, (2) quantification of the DNA (3) amplification of specific regions on the human chromosomes, (4) analysis of the sequence of amplified DNA, and (5) comparison with possible suspects whose DNA has been banked in the National DNA Data Bank (NDDB) or whose DNA has been collected as part of the investigation.

Il y a un résumé en français ici.

Keywords
Forensic Analysis;Bioweapons, DNA;criminal investigation
Report Number
DRDC-CSS-CR-2011-22 — Contractor Report
Date of publication
01 Oct 2011
Number of Pages
63
DSTKIM No
CA036048
CANDIS No
535488
Format(s):
Electronic Document(PDF)

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