STUDIES ON PLAQUE VARIANTS OF COXSACKIEVIRUS B5 BY BURST ANALYSES

Authors
  1. Konowalchuk, J.
  2. Speirs, J.I.
Corporate Authors
Defence Chemical Biological and Radiation Labs, Ottawa ONT (CAN)
Abstract
Propagation of coxsackievirus B5 on cell lines revealed two variants, one that yields small plaques and is stable and another that is large but variable in size. Multiple-burst studies on the large-plague pool showed the existence of two different population sections. Analysis of a sample from a plaque belonging to the small population section showed a progeny of small plaques while a similar analysis from a plaque in the large population section produced plaques of varying size but whose mean plaque diameter resembled that of the parent culture. Repeated selection for smallness from plaques in the large population section resulted in small plaques and a shift from the large to the small population section.
Report Number
DCBRL-511 — Reprint; Previously Catalogued as DSIS 67-04189
Date of publication
01 Jan 1967
Number of Pages
9
Reprinted from
Canadian Journal of Microbiology, vol 13, 1967, p 167-172
DSTKIM No
89-01267
CANDIS No
59199
Format(s):
Hardcopy;Originator's fiche received by DSIS

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