THROMBOPHLEBITIS FOLLOWING INTRAVENOUS GLUCOSE IN THE COLD

Authors
  1. Vallerand, A.L.
  2. Kavanagh, M.F.
Corporate Authors
Defence and Civil Inst of Environmental Medicine, Downsview ONT (CAN)
Abstract
In an effort to characterize the role of carbohydrate metabolism during the hypermetabolic state associated with whole body cooling, oral (n=6) and intravenous (iv; n=3) glucose tolerance tests (GTT) were performed in nude subjects. Unexpectedly, 1-2 wks after the completion of their iv GTT (50% dextrose) in the cold, superficial thrombophlebitis was diagnosed in all 3 subjects. Since this complication was not observed in further testing with isotonic iv solutions under identical conditions in the cold as above, we conclude that the adverse reaction is the result of an interaction between whole body cooling or vasoconstriction and the hypertonicity of the dextrose solution.
Report Number
DCIEM-88-N-57 — Reprint
Date of publication
15 Apr 1989
Number of Pages
3
Reprinted from
Aviation, Space, and Environmental Medicine, 1989, no 60, p 349-351
DSTKIM No
89-02383
CANDIS No
60289
Format(s):
Hardcopy;Originator's fiche received by DSIS

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