STAPHYLOCOCCAL AUREUS ENTEROTOXIN A: PARTIAL CHARACTERIZATION OF AN N-TERMINAL PEPTIDE

Authors
  1. Micusan, V.V.
  2. Lacroix, M.
  3. Bhatti, A.R.
Corporate Authors
Defence Research Establishment Suffield, Ralston ALTA (CAN);Institut Armand Frappier, Laval QUE (CAN)
Abstract
A peptide (NH2-Ser-Glu-Lys-Ser-Glu-Glu-Ile-Asn-Glu-Lys-Gly-Lys) from the N-terminal sequence of staphylococcal enterotoxin A (SEA) was synthesized and conjugated to bovine serum albumin (BSA). When injected into rabbits, this conjugate induced antibodies which reacted with the native SEA molecule. These antibodies did not cross-react with other enterotoxins. However, the obtained anti-peptide antibodies were less efficient in detecting SEA than antibodies raised to the whole molecule.
Report Number
DRES-M-1259 — Memorandum
Date of publication
15 May 1989
Number of Pages
16
DSTKIM No
89-03069
CANDIS No
60970
Format(s):
Hardcopy;Originator's fiche received by DSIS

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