INFLUENCE OF THEOBROMINE ON HEAT PRODUCTION AND BODY TEMPERATURES IN COLD-EXPOSED HUMANS: A PRELIMINARY REPORT

Authors
  1. Vallerand, A.L.
  2. Wang, L.C.H.
  3. Jacobs, I.
Corporate Authors
Defence and Civil Inst of Environmental Medicine, Downsview ONT (CAN);Alberta Univ, Edmonton ALTA (CAN) Dept of Zoology
Abstract
The influence of theobromine was investigated in eight healthy young male subjects during two semi-nude exposures to cold air (3h, 7C, 1 m/s wind speed). The ingestion of theobromine (7.5 mg/kg at min 0; double-blind placebo-controlled trial) produced two different types of responses, as shown by a significant interaction between the effect of group (responders vs non-responders) and the effect of drug treatment (placebo vs theobromine) on the rate of decrease in mean body temperatures (T sub b). In conclusion, the results are interpreted as indicating that the ingestion of theobromine in subjects capable of producing a relatively high metabolic response to the cold, significantly improves cold tolerance by increasing heat production, mainly from a greater lipid utilization.
Report Number
DCIEM-89-RR-50 — Research Report
Date of publication
15 Nov 1989
Number of Pages
34
DSTKIM No
90-00566
CANDIS No
62844
Format(s):
Hardcopy;Originator's fiche received by DSIS

Permanent link

Document 1 of 1

Date modified: