CAPILLARY COLUMN AMMONIA CHEMICAL IONIZATION GC-MS AND GC-MS/MS DETECTION OF CHEMICAL WARFARE AGENTS IN A COMPLEX AIRBORNE MATRIX

Authors
  1. D'Agostino, P.A.
  2. Provost, L.R.
  3. Brooks, P.W.
Corporate Authors
Defence Research Establishment Suffield, Ralston ALTA (CAN);Institute of Sedimentary and Petroleum Geology, Calgary ALTA (CAN)
Abstract
The chemical warfare agents, sarin and soman, were detected and confirmed during full scanning capillary column ammonia chemical ionization mass spectrometry at nanogram levels in spiked extracts of a diesel exhaust environment sampled onto the charcoal of a Canadian C2 respirator canister. The selectivity of ammonia chemical ionization enabled the use of selected ion monitoring and resulted in detection limits of 40 pg and just above 500 pg for sarin and soman respectively in this extract. This matrix, typical of what might be encountered under battlefield conditions, was used to evaluate capillary column ammonia chemical ionization tandem mass spectrometry as a possible verification technology. Chemical interferences were reduced and significantly better detection limits, 15 pg and 80 pg for sarin and some respectively, were obtained during GC-MS/MS analysis of these agents in the presence of numerous interfering diesel exhaust and charcoal bed components.
Report Number
DRES-M-1305 — Memorandum
Date of publication
15 Jan 1990
Number of Pages
29
DSTKIM No
90-02030
CANDIS No
64295
Format(s):
Hardcopy;Originator's fiche received by DSIS

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