DEVELOPMENT OF HIGH-RESOLUTION SEPARATORY TECHNIQUES AND MASS SPECTROMETRIC METHODS FOR THE VERIFICATION OF SAXITOXIN AND TETRODOTOXIN IN WATER AND SOIL

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Authors
Corporate Authors
Defence Research Establishment Suffield, Ralston ALTA (CAN);National Research Council of Canada, Halifax NS (CAN) Inst for Marine Biosciences
Abstract
Nature produces many compounds that are highly toxic to humans. Among the most toxic are certain metabolites produced by marine organisms; these include saxitoxin (STX), a member of a related family of compounds responsible for paralytic shellfish poisoning (PSP, the "red-tide" shellfish poisoning), and tetrodotoxin (TTX), the puffer fish toxin. These toxins have been recognized by the UN as potential chemical warfare agents. It is important therefore to have available analytical methods for verification procedures with respect to chemical warfare controls agreements. The extremely high toxicity of these marine toxins implies that such analytical methods must be capable of detecting, identifying, and if possible quantifying, the target compounds present at trace levels in complex matrices. The present document thus represents an interim report on work done at IMB on instrumental techniques for trace analysis of these highly polar, thermally labile toxins.
Report Number
DRES-CR-32-91 — Contract Report (Interim)
Date of publication
01 Jan 1991
Number of Pages
31
DSTKIM No
91-03378
CANDIS No
70569
Format(s):
Electronic Document(PDF)

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