VIRUS ENHANCEMENT WITH A GROWTH PRODUCT OF STREPTOMYCES SCABIES. II. INCREASED RELEASE OF COXSACKIEVIRUS B5 FROM HEp-2 MONOLAYERS TREATED WITH SCABEN

Authors
  1. Konowalchuk, J.
  2. Speirs, J.I.
Corporate Authors
Defence Chemical Biological and Radiation Establishment, Ottawa ONT (CAN)
Abstract
A single-cycle infection of scaben-treated HEp-2 monolayers with coxsackievirus B5showed no increase in total virus yield but an enhancement of virus release which was correlated with an earlier cytopathic effect. These findings were further substantiated in multiple-cycle infections where enhanced release shortened the period necessary to infect all the cells in a monolayer, thus, in effect, producing higher yields of virus in a shorter time.
Report Number
REP559 —
Date of publication
15 May 1968
Number of Pages
4
Reprinted from
Can J of Microbiol, vol 14, no 10, 1968, p 1111-1114
DSTKIM No
69-01126
CANDIS No
72204
Format(s):
Hardcopy;Originator's fiche received by DSIS

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