SEX DIFFERENCES IN THE ACUTE TOXICITY OF ORGANOPHOSPHORUS CHOLINESTERASE INHIBITORS

Authors
  1. Coleman, I.W.
  2. Patton, G.E.
Corporate Authors
Defence Research Establishment Ottawa, Ottawa ONT (CAN)
Abstract
The toxicity of sarin, tabun, DSDP and soman in male and female mice, rats and hamsters has been determined. There were no observed sex differences in the toxicities of soman and tabun in the species studied. Sarin and DSDP were equally toxic to both sexes of rats and hamsters, although both agents were found to exhibit a small but highly significant increase in toxicity for male mice.
Keywords
Anticholinergics;Sarin;Tabun;DSDP;Soman
Report Number
R576 —
Date of publication
15 Mar 1969
Number of Pages
6
DSTKIM No
69-04987
CANDIS No
74066
Format(s):
Hardcopy;Originator's fiche received by DSIS

Permanent link

Document 1 of 1

Date modified: