R&D Study: Coagulopathy in Trauma – A Comparative Study between ROTEM® and TEG®


  1. Rizoli, S.
Corporate Authors
Defence Research and Development Canada, Toronto Research Centre , Toronto ON (CAN)
The purpose of this final report is to provide you with a description of the complete project, details of design, tests carried out, results obtained and evaluation of results, conclusions reached and suggestions for further work. This report presents an overview of the findings of the three‐year project “R&D Study: Coagulopathy in Trauma: a Comparative Study between ROTEM ® and TEG ®. The aim of this study has been to assess the usefulness of rotational thromboelastometry (ROTEM®) in assessing coagulopathy of trauma, in patients predicted to receive MT who are included in the PROPPR trial. Additionally this study aimed to evaluate the ability of ROTEM®/TEG® to guide transfusion and predict outcomes. It was a comparative analysis including a cohort of 30 trauma patients enrolled in the PROPPR randomized controlled trial. This cohort of injured patients had their coagulation status evaluated by ROTEM®, TEG® and SBCT simultaneously. The patients will be their own controls as the ROTEM® values will be compared to those obtained from TEG® AND SBCT, in relation to the outcomes. Test characteristics including sensitivity for the diagnosis of coagulopathy for TEG® and ROTEM® PARAMETERS, as well as for SBCT’s will be determined. ROC and regression analyses would have been used to assess the ability of TEG®, ROTEM® and SBCT’s to predict transfusion requirements. Turnaround time, robustness and ease of use for TEG®, ROTEM® and SBCT’s will be compared.
trauma induced coagulopathy;teg;rotem;blood transfusion
Report Number
DRDC-RDDC-2015-C233 — Contract Report
Date of publication
25 Oct 2015
Number of Pages
Electronic Document(PDF)

Permanent link

Document 1 of 1

Date modified: