Market place survey of diagnostic platforms suitable for field hospital or field-use settings – Analysis of suitability for the detection of pre-symptomatic infection-related biomarkers

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Authors
  1. Christopher, M.E.
  2. Bader, D.E.
Corporate Authors
Defence Research and Development Canada, Suffield Research Centre, Ralston AB (CAN)
Abstract
Defence Research and Development Canada – Suffield Research Centre (DRDC – Suffield Research Centre) has a project examining the suitability of using host-specific factors (biomarkers) as an indication of infection, prior to symptom development in an exposed individual. Should suitable biomarkers be identified following rigorous examination to ensure that they are specific to infection and sensitive enough to be useful, assays for these biomarkers will need to be transitioned from the research laboratory to the Canadian Armed Forces (CAF). Diagnosis of infection with a pathogen, prior to symptom development, could aid the CAF in screening individuals or groups that need to be treated, isolated, or returned to normal duties. During deployment, diagnosis of CAF members exposed or suspected of being exposed to serious pathogenic agents would be done by medical staff in a field hospital or at a forward operating base (FOB), or in the field by the operators themselves in order to identify at-risk individuals or at-risk populations. In order for any diagnostic (Dx) test to be useful under these conditions, the Dx equipment must, at minimum, have a relatively small footprint; have limited consumables and power requirements; and be relatively easy to operate, with minimal maintenance and minimal operator training burden. In order to identify Dx platforms that could meet these requirements, DRDC – Suffield Research Centre initiated a contract to survey Dx platform vendors, and i

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Keywords
diagnostic platforms;biomarkers;pre-symptomatic;forward operating base;field hospital;hand-held;field-use
Report Number
DRDC-RDDC-2017-R066 — Scientific Report
Date of publication
01 May 2017
Number of Pages
39
DSTKIM No
CA055095
CANDIS No
805481
Format(s):
Electronic Document(PDF)

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