ETHANOL POTENTIATION OF CHOLINE, ACETYLCHOLINE, CARBACHOL AND PHENYLTRIMETHYLAMMONIUM CONTRACTIONS IN THE CHICK BIVENTER CERVICIS MUSCLE

Authors
  1. Clement, J.G.
Corporate Authors
Defence Research Establishment Suffield, Ralston ALTA (CAN)
Abstract
Pretreatment of chick biventer cervicis preparations with ethanol (290 mM) potentiated the EC sub 50 of choline, acetylcholine, carbachol and phenyltrimethylammonium 91%, 319%, 97% and 213%, respectively. Perhaps this interaction of ethanol and neurotransmitter could contribute to the effects on coordination and motor activity produced by ethanol in vivo.
Report Number
TP-505 —
Date of publication
01 Jan 1980
Number of Pages
4
Reprinted from
European J of Pharmacology, vol 61, 1980, p 195-198
DSTKIM No
80-01189
CANDIS No
88887
Format(s):
Hardcopy;Originator's fiche received by DSIS

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