EXPERIMENTS ON THE MECHANISM OF MENIERE ATTACKS

Authors
  1. Dohlman, G.F.
Corporate Authors
Defence and Civil Inst of Environmental Medicine, Downsview ONT (CAN);Toronto Univ, Toronto ONT (CAN) Dept of Otolaryngology
Abstract
The pattern of response decline following semicircular canal stimulation corresponds to a mechanical process. The process is the elastic recoil of the hairs of the sensory cells. The response decline is the same, whether the endolymph-cupula system is patent or mechanically maintained in a displaced position. The role of the bending of the entire cupula as the principle factor is excluded for the response and its decline. Repeated endolymph displacements immediately after each decline of response always result in an equal response and its decline.This rules out the depletion of a chemical mediator as a cause for the response decline. Indentations of the sidewalls of the ampulla result in reactions suggesting that the ampulla is filled with a loose gel secreted by the planum semilunatum cells.
Report Number
REPR-75-X-12 —
Date of publication
01 Jan 1977
Number of Pages
22
Reprinted from
J of Otolaryngology, vol 6, no 2, 1977, p 135-156
DSTKIM No
77-02984
CANDIS No
99731
Format(s):
Hardcopy;Originator's fiche received by DSIS

Permanent link

Document 1 of 1

Date modified: